Serous membranes, particularly articular synovia, can become irritated, leading to effusion. Pain is throbbing; even the slightest movement may cause it to increase, but absolute immobility may improve it. Acute neuralgia, cramp-like as well as spasmodic, can be felt in the back and loins, forcing the patient to sit up. The joints are swollen, warm, but benefits from rest. BM 199 helps reduce discomfort and disability related to muscle, tendon, joint, bone, or nerve, including rheumatoid arthritis, degenerative, myositis, neuritis, lumbago, sciatica and gout.