Chronic renal failure is triggered by disease or a hereditary disorder in the kidney. Decreased urine output, need to urinate at night, easy bruising, blood in the vomiting or in the stools, drowsiness, lethargy, confusion, delirium, muscle twitching or cramps, urimic frost (deposits of white crystals in and on the skin), decreased sensation in the upper and lower extremities, paleness, nail abnormalities, appetite loss and coma. BM 64 C.R.F is proven to reduce all of these symptoms, helping keep the body's fluid and electrolyte imbalance in check through its comprehensive formula.